Group Seed Fund Award

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Neurorehabilitation Research

Teachers College, Columbia University

Huntington's Study Group Seed Fund Award

We are pleased to annouce that Dr. Lori Quinn has received a 2017 Huntington's Study Group Seed Fund Award. Thanks to the funding by the Huntington Study Group, this study will begin recruitment April 2017.

This study will implement a clinic-based physical activity coaching intervention in people with pre-manifest and early stage HD at Columbia University Huntington’s Disease Center of Excellence. This study is an extension of Engage-HD (ISRCTN65378754) developed and evaluated a physical activity behavioural change intervention.  In a study conducted in the UK, this intervention was found to be feasible and accept to patients with mid stage HD, and those in the intervention group demonstrated higher levels of self-reported physical activity, self-efficacy for exercise, and cognition (SDMT) compared to a social contact control group. We have not yet applied this intervention in pre-manifest and early stage HD, where we believe it is most critical to engage in exercise. To date, no study has prospectively evaluated a physical activity intervention to facilitate exercise uptake in these earliest stages. 

This study will explore the feasibility and acceptability of the Engage-HD intervention in individuals with pre-manifest and early stage HD, and using the data will make relevant adaptations to prepare for a US-based Phase II evaluation.  We will recruit 14 individuals (7 pre-manifest and 7 early stage) with genetically confirmed Huntington’s disease.  Individuals will undergo a one-hour coaching session, followed by 3 remote video conferences over a 4 monthe period to facilitate exercise uptake and physical activity.  Participants will be given a disease-specific physical activity workbook and will be given a wearable physical activity monitor to monitor activity over the 4-month intervention.   Participants will undergo assessments at baseline and post intervention, which will include the IPAQ, Lifespace Assessment, and UHDRS TMS, Functional assessment and cognition.  

Published Friday, Jan. 27, 2017

Huntington's Study Group Seed Fund Award

This study will implement a clinic-based physical activity coaching intervention in people with pre-manifest and early stage HD at Columbia University Huntington’s Disease Center of Excellence. This study is an extension of Engage-HD (ISRCTN65378754) developed and evaluated a physical activity behavioural change intervention.  In a study conducted in the UK, this intervention was found to be feasible and accept to patients with mid stage HD, and those in the intervention group demonstrated higher levels of self-reported physical activity, self-efficacy for exercise, and cognition (SDMT) compared to a social contact control group. We have not yet applied this intervention in pre-manifest and early stage HD, where we believe it is most critical to engage in exercise. To date, no study has prospectively evaluated a physical activity intervention to facilitate exercise uptake in these earliest stages. 

This study will explore the feasibility and acceptability of the Engage-HD intervention in individuals with pre-manifest and early stage HD, and using the data will make relevant adaptations to prepare for a US-based Phase II evaluation.  We will recruit 14 individuals (7 pre-manifest and 7 early stage) with genetically confirmed Huntington’s disease.  Individuals will undergo a one-hour coaching session, followed by 3 remote video conferences over a 4 monthe period to facilitate exercise uptake and physical activity.  Participants will be given a disease-specific physical activity workbook and will be given a wearable physical activity monitor to monitor activity over the 4-month intervention.   Participants will undergo assessments at baseline and post intervention, which will include the IPAQ, Lifespace Assessment, and UHDRS TMS, Functional assessment and cognition.  

How This Gift Connects The Dots
 
Scholarships & Fellowships
 
Faculty & Programs
 
Campus & Technology
 
Financial Flexibility
 
Engage TC Alumni & Friends