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Teachers College, Columbia University
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Laboratory for the Study of Upper Airway Dysfunction

ACTIVE- FUNDED

Michael J Fox Foundation

Novel Management of Airway Protection in Parkinson's disease: A clinical trial

The overarching aim of the proposed study is to determine the efficacy of two distinct intensive rehabilitation paradigms, expiratory muscle strength training (EMST) and sensorimotor treatment for airway protection (smTAP), on airway protective clinical outcomes in persons with PD and dysphagia.  We anticipate our results will lead to reductions in the risks associated with airway protective deficits

Role: Principal Investigator (PI)

National Institutes of Health, National Institute on Deafness and Other Communication Disorders - R21

Airway protection deficits according to stimulus type in Parkinson’s disease

The objective of this study is to test the efficacy of a novel screening device to detect airway protective deficits in a large cohort of people with Parkinson’s disease.
Role: Sub-Investigator; PI for Sub-contract to Columbia University

PI: Karen Hegland, University of Florida

Teachers College, Columbia University - Provost Investment Fund 2015

Clinical-Research Neurorehabilitation Center at Teachers College, Columbia University

This application proposes the creation of the Clinical-Research Neurorehabilitation Center (CRNC) at Teachers College, Columbia University.  The applicants of this proposal, both licensed speech-language pathologists (SLPs) and experienced clinical researchers in adult neurogenic populations, are uniquely qualified to oversee the creation and growth of a center focused on neurorehabilitation within the context of an academic model.

Role: Co-PI

Teachers College, Columbia University - Provost Investment Fund 2016

Clinical Research Initiative in Rehabilitation for Neurodegenerative Diseases

This application proposes an initiative aimed at strengthening clinical research for rehabilitation in neurodegenerative disease at Teachers College.  The funding will be used to enhance the collaboration between the Neurorehabilitation Research Laboratory and the Upper Airway Dysfunction Laboratory (both housed in the Department of Biobehavioral Sciences) and the Movement Disorders Division at Columbia University Medical Center.  The goal is to promote access to critical patient populations which will enhance and facilitate the clinical research agenda in rehabilitation for neurodegenerative diseases at Teachers College and Columbia University.  

Role: Co-PI

Northern Health Foundation – Victoria, Australia

Using Expiratory Muscle Strength Training (EMST) for dysphagia in PD in the community setting

The primary objective of this study is to assess whether an intensive home program of EMST can improve swallowing safety for individuals with Parkinson’s disease in the community setting.  
Role: Primary Mentor

PI: Marinda Brooks

COMPLETED

Clinical and Translational Science Institute – NIH KL2 Award

NIH (NCATS) CTSA awards to the University of Florida UL1TR000064 and KL2TR000065
Airway protective mechanisms and Deep Brain Stimulation Surgery in Parkinson’s disease

The overarching aim of the proposed study is to prospectively study the effects of unilateral subthalamic nucleus (STN) vs. globus pallidus interna (GPi) deep brain stimulation (DBS) surgery in Parkinson’s disease on swallowing and cough function. This aim will be achieved by testing the swallowing and cough function of 40 consecutive patients with PD receiving DBS surgery.

Role: KL2 Fellow/Principal Investigator  

Parkinson’s Study Group

Effects of Singing on Speech and Swallow in Patients with Parkinson’s Disease

Role: Sub-Investigator
PI: Elizabeth Stegemoller, PhD

BTI Purdue

Use of SpeechVive to Treat Hypophonia in Parkinson’s Disease

Role: Sub-Contract – University of Florida PI
PI: Jessica Huber, PhD (Purdue University)